Depressive personality disorder (DPD) is a mental health condition characterized by persistent feelings of sadness, worthlessness, and a negative outlook on life. It affects approximately 2-3% of the population and can have a significant impact on a person's quality of life. In this article, we will present a case of a patient with DPD and discuss how this condition can be diagnosed and treated. Case Presentation: The patient, a 28-year-old woman, presented to our clinic with a history of chronic sadness, hopelessness, and lack of self-confidence. She reported feeling “stuck” in her negative thoughts and emotions and expressed a deep sense of emptiness and lack of purpose in life. She had difficulty sleeping, lost interest in activities she once enjoyed, and experienced weight loss over the past few months. Upon evaluation, the patient met the diagnostic criteria for DPD as outlined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). In particular, she demonstrated a widespread pattern of depressive symptoms, including low self-esteem, pessimism, and lack of pleasure in most activities. She also reported a history of childhood trauma that may have contributed to the development of her DPD. Treatment: The patient initially began taking an antidepressant, which helped improve her mood and reduce some of her symptoms. However, we also recommended that she participate in psychotherapy to address the underlying psychological factors contributing to her condition. Specifically, we recommended psychoanalytic treatment, which involves examining unconscious thoughts and emotions to identify the root causes of mental disorder. Through therapy, the patient was able to gain insight into her negative thoughts and begin to challenge them. She also learned strategies to cope with her symptoms, such as mindfulness and relaxation techniques. Over time, the patient's symptoms gradually improved and she reported feeling less pessimistic and more engaged in life. She also reported improved relationships with her family and friends and an increased sense of self-worth. Conclusion: DPD can be a challenging disease to treat, but with the right approach, patients can achieve significant improvements in their quality of life. As demonstrated in this case study, a combination of medications and psychotherapy can be effective in treating symptoms and addressing underlying psychological factors. If you or someone you know is struggling with DPD, it is important to seek professional help to receive an accurate diagnosis and appropriate treatment. With the right support, it is possible to overcome this condition and build a brighter future..